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Antimicrobial resistance in Neisseria gonorrhoeae: history, molecular mechanisms and epidemiological aspects of an emerging global threat BJM
Costa-Lourenço,Ana Paula Ramalho da; Santos,Késia Thaís Barros dos; Moreira,Beatriz Meurer; Fracalanzza,Sergio Eduardo Longo; Bonelli,Raquel Regina.
ABSTRACT Neisseria gonorrhoeae is the agent of gonorrhea, a sexually transmitted infection with an estimate from The World Health Organization of 78 million new cases in people aged 15-49 worldwide during 2012. If left untreated, complications may include pelvic inflammatory disease and infertility. Antimicrobial treatment is usually effective; however, resistance has emerged successively through various molecular mechanisms for all the regularly used therapeutic agents throughout decades. Detection of antimicrobial susceptibility is currently the most critical aspect for N. gonorrhoeae surveillance, however poorly structured health systems pose difficulties. In this review, we compiled data from worldwide reports regarding epidemiology and antimicrobial...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Neisseria gonorrhoeae; Surveillance; Resistance mechanisms.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000400617
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The Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) identification versus biochemical tests: a study with enterobacteria from a dairy cattle environment BJM
Rodrigues,Naiara Miranda Bento; Bronzato,Greiciane França; Santiago,Gabrielli Stefaninni; Botelho,Larissa Alvarenga Batista; Moreira,Beatriz Meurer; Coelho,Irene da Silva; Souza,Miliane Moreira Soares de; Coelho,Shana de Mattos de Oliveira.
Abstract Mastitis adversely affects milk production and in general cows do not regain their full production levels post recovery, leading to considerable economic losses. Moreover the percentage decrease in milk production depends on the specific pathogen that caused the infection and enterobacteria are responsible for this greater reduction. Phenotypic tests are among the currently available methods used worldwide to identify enterobacteria; however they tend to misdiagnose the species despite the multiple tests carried out. On the other hand The Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) technique has been attracting attention for its precise identification of several microorganisms at species level. In...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bovine mastitis; Enterobacteria identification; Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000100132
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